Linezolid-Associated Peripheral Neuropathy

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Linezolid-associated peripheral and optic neuropathy in children.

OBJECTIVE Peripheral neuropathy (PN) and optic neuropathy (ON) associated with linezolid use are described in the adult literature; however limited information is available in pediatrics. The purpose of this communication is to summarize pediatric cases of linezolid-associated neuropathy and to increase awareness of these neurologic side effects so that clinicians can most appropriately balance...

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Reversal of linezolid-associated cytopenias, but not peripheral neuropathy, by administration of vitamin B6.

OBJECTIVES We sought to determine if vitamin B6 therapy would reverse linezolid-associated cytopenias and/or peripheral neuropathy. PATIENTS AND METHODS We have recently treated two patients with disseminated Mycobacterium abscessus infections with prolonged (> or =9 month) courses of linezolid. Both patients developed cytopenias related to linezolid, and one patient also developed peripheral...

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Linezolid-induced optic neuropathy

Many systemic antimicrobials have been implicated to cause ocular adverse effects. This is especially relevant in multidrug therapy where more than one drug can cause a similar ocular adverse effect. We describe a case of progressive loss of vision associated with linezolid therapy. A 45-year-old male patient who was on treatment with multiple second-line anti-tuberculous drugs including linezo...

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Peripheral neuropathy associated with fluoroquinolones.

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ژورنال

عنوان ژورنال: Mayo Clinic Proceedings

سال: 2004

ISSN: 0025-6196

DOI: 10.4065/79.7.927